Hand-Schuller-Christian disease is reactive granulomatous lesion with histiocytic proliferation, the cause of which is unknown. Recently, we experienced a case in a 3 years old female with polydipsia and polyuria. We established the diagnosis with clinical features, radiologic examination and bone biopsy- Histiologic examination of frontal bone showed mild to moderate infiltration of eosinophils, lymphocytes, plasma cells and large histioytes and fibrosis. Similiar cases reported in... |
We reviewed 10 cases of Tuberous sclerosis clinically during the last 2 years from March 1980 to June 1982 and the following conclusion was obtained: 1) The younger children may have cafe au lait spots and depimentation with seizure and psychomotor retardation as the diagnostic clues, while the older one may have Adenoma sebaceum. 2) Computerized tomography of brain is essential for diagnosis as it discloses... |
We observed a case of congenital hypoplastic anemia in 22 months old Korean male infant whose clinical and hematologic improvement was achieved by administration of prednisone. A brief review of related literatures was made. |
A statistical assessment was carried out in two hundreds and eighty three inpatients and outpatients and fifteen mothers who were subjected to chromosomal analysis at Department of Pediatrics, Seoul National University Hospital, from January 1977 to February 1982. The following results were obtained: 1) Age distribution revealed 65.8% of all children subjected to chromosomal analysis to be: under 2 years of age. The number of... |
We experienced a case of Hypereosinophilic syndrome with congestive heart failure in 15 month old girl. The clinical, hematologic and E.C.G. findings were compatible with hype- reosinophilic syndrome. She was treated with oxygen, digoxine, antibiotics and mebendazole. But on 8th day of admission she suddenly died. A brief review of the related literature was made on this subject. |
Authors have observed a case of congenital hypoplastic anemia in 18 months old male patient who was diagnosed through the bone marrow aspiration. The liver was enlarged and the biopsy specimen disclosed iron deposition in the hepatocyte, which was thought to be resulted from multiple blood transfusion and administration of iron preparation. A brief review of related literature was made. |
We have seen 96patients who were admitted with purpura to the Pediatric Department of Kwangju Christian Hospital during the period of 10 years from Jan., 1971 to Dec., 1980. The following observations were made; 1) Leukemia(26 cases, 27.0%) was the most common underlying disease, followed by allergic purpura (25 cases, 26.0%), idiopathic thrombocytopenic purpura (22 cases, 22.9%), Aplastic Anemia (13 cases, 13.5%), sepsis (5 cases,... |
A case of aplastic anemia following hepatitis is presented. A 13-year-old boy was admitted due to unexpected bleeding manifestations after recovery from hepatitis. There was marked pancytpenia and examiation of bone marrow revealed remarkable hypoplasia. His clinical course became worsened despite antibiotics, multiple transfusions and therapy with corticosteroid, oxymetholone. Related literatures are also briefly reviewed. |
The Gianotti-Crosti syndrome is an. infrequently recognized disorder with distinctive clinical features. We have experienced two cases of Gianotti-Crosti syndrome diagnosed by clinical manifestation, laboratory data and histopathologic finding of skin. Case one; An 18-month-old girl was admitted to the pediatric ward with the chief complaint of erythematous rash. Its onset was preceded by an. upper respiratory tract infection. She had a wide spread erythematous... |
First admission; A 4 year old male patient was admitted with progressive swelling and tenderness of left scrotum since birth. Left simple orchiectomy was performed. The histolo- gic finding was testicular yolk sac tumor. Second admission; 2 years later. The patient was readmitted with migrating pain and limitation of motion of lower extremities. Lung metastasis (LLL extending to lingular lobe) was appeared. During chemotherapy, he... |
The survey was performed on 418 cases of mothers who were visited our pediatric out- patients and well baby clinics from January to July of 1981. The results of this survey were as follows: 1. The differentation of weight, height, chest circumference between the mothers of arti- ficial or mixed feeding and breast feeding was not seen. 2. The average nipple length of mothers of breast feeding,... |
This experiment was carried out to investigate the effects of anticancer drugs on the phagocytic function of reticuloendothelial system. The phagocytic activity was assessed by- means of carbon clearance method, after intravenous injection of vincristine(5 pg or 25 y^g/lOO gm of body weight) and adriamycin (70 pg or 350 ^g/100 gm of body weight) through one, two, and three times at the interval of... |
An accurate evaluation of the size of the genitalia and its function is mandatory in judging abnormal growth of external genitalia from birth to adolescence as well as adulthood. This study was carried out to establish the standard values of penile and testicular sizes for normal Korean boys. Nine hundred and fifty-four Korean boys from birth to 15 years of... |
The congenital mesoblastic nephroma is the most common renal neoplasm seen in the first few months of life. This tumor usually benign, but local recurrences and metastases have been reported, and treatment is total nephrectomy. This entity must be differentiated from Wilm's tumor so as to avoid unnecessary postoperative irradiation and chemotherapy. Recently, we experienced a case of congenital mesoblastic... |
Hereditary spastic paraplegia is a familial disorder which is inherited by autosomal dominant, autosomal recessive or sex linked pattern. We experienced a family who has hereditary spastic paraplegia with mental retardation and extrapyramidal symptom that is thought inherited by autosomal dominant inheritance pattern. A review of literatures was made briefly. |
Polycstic kidney was rare problem of pediatric disease category. We have experienced one case of polycstic kidney(Potter type I) with pulmonary hypoplasia who born after 35 weeks of gestation to a 34 year-old mother. The clinical course of this infant was characterized by respiratory difficulty with apnea, cyanosis and marked abdominal distension. Chest X-Ray film showed no airation in the... |
The authors reviewed 729 Pediatric inpatients in this Hospital during 3 years period from Jan. 1978. To Dec. 1980. The results were obtained as follow: 1. The male to female ratio was 2.2:1. 2. Distrstribution of cases as follows:; Infectious and parasitic diseases 39.5%, diases of the respiratory system 23.87% and diseases of the genitourinary system 10.29%, in turn, listed... |
We experienced a case of anterior mediastinal teratoma in 26 month old boy with 2 month history of cough and dyspnea. The diagnosis was easily established by chest CAT which revealed calcific densities, while plane radiographs of chest revealed no evidence of calcification. Operation was done with good result and remained in good condition thereafter. A brief of the related... |
A study was made to see the family back ground abandonment of mother's right, clinical and laboratory examination(urinalysis, blood examination, tuberculous skin test, VDRL, PKU screening test and chest X-ray) on 1,793 infants and children in an institure for foreign adoption. The results were as follows: 1) Gilrs were much more predominant than boys with male to female ratio of... |
Leukemic infiltration of the testes has been relatively rare disease. But increased survival due to advance in the treatment of childhood leukemia has been associated with an increase in incidence of leukemic infiltration of the tests. Six of 66 male children with acute lymphocytic leukemia and 2 of 2 male children with leukemic transformation on non-Hodgkin's lymphoma, who have been... |
We experienced a cass of Letterer-Siwe disease in 2 month old infant. The patient was presented charateristic clinical findings such as hepatosplenomegaly, petechia, anemia, gene-ralized lymphadenopathy, and lung infiltration. The diagnosis was confirmed by lymphnode biopsy and bone marrow aspiration, which was compatible to Letterer-Siwe disease. A poor prognostic factor in Histiocytosis X is younger age (below 18 month), hepatospleno-megaly, anemia,... |
Tuberous sclerosis is an inherited neurocutaneous disorder characterized by seizures, mental ratardation, cutaneous lesions and visceral hamartomas. The usual renal lesion in tuberous sclerosis is the angiomyolipoma which is a hamartomas, but polycystic kidney is relatively rare. We confirmed tuburous sclerosis on the base of the radiological and clinical characterics in 8 years old girl of mental deficiency with four... |
This is the clinical statistics concerning the admissions in the Pediatric Department of the Chosun University Hospital during the past 5 years from Jan. 1975 to Dec. 1979. All the patients were classified by y Classification of Disease by W.H.O. The Obtained results are as follows: 1. Total number of admission during 5 year period were 3249 cases, of which... |
The 15 year-old female patient was admitted with the complaints of moon face, obesity and short stature. She has received steroid therapy since 11 years ago at home to control joint pain due to rheumatoid arthritis. The diagnosis was confirmed by history of long-term steroid therapy, characteristic clinical features, biochemical studies and radiological studies. In radiological studies, superior mediastinal widening,... |
Histiocytic Medullary Reticulosis(H.M.R.) is a rapidly progressing fatal disease seen most often in adults, but it has been reported in children younger than 15 years of age. H.M.R. is clinically characterized by fever, wasting generalized lymphadenopathy and hepatosplenomegaly. In the terminal stage, jaundice, purpura, anemia and pancytopenia are all present with or without skin involvement. Cardinal pathologic features are systemized... |
Pneumomediastinum, pneumothorax and subcutaneous emphysema are uncommon in pediatric practice, but they may be rarely ocured in association with respiratory distress and excessive ressusciation in the neonatal period, and as a complication of bronchial asthma, measles in childhood. And also, there was a report of a few cases that developed to pneumomediastinum and subcutaneous emphysema caused by vomiting in patient... |
We report 1 case of Fanconi's anemia which has severe pancytopenia, PDA, hypoplatic right thumb and cryptorchism with a brief review of related literature and references. |
Cysticercosis infestation is a cosmopolitan disease. Recently we experienced six cases of intracranial cysticercosis in childhood, three of them were male and their age distributed from 2 to 15 years. Their main clinical manifestations were symptoms of increased intracranial pressure signs and other neurological sings as well, In diagnostic procedures, brain C-T scan was performed in all cases and Conray... |
A statistical study on 135 cases of acute poisoning who were treated in Pediatric department of Soon Chun Hyang College Hospital from May, 1974 to August, 1980 was performed. The results are as follows: 1. Seasonal incidence was more prevalent in summer. (from June to August, Table 2) 2. It occurred more frequently in male than female and high incidence... |
Serum levels of T3, T4, TSH, 24-h RAIU and Thyroid antibodies were examined in 13 cases of chronic lymphocytic thyroiditis who were diagnosed at the pediatric department of Yonsei University hospital during the period from 1978 to 1980. The results were as follows: 1. The age distribution was dispersed between 8 and 15 years of age and all the cases... |